PRIO – A tool for Risk Reduction of Chemicals

Overview table

The following tables provide an overview of the substance properties that characterise the substances at the two levels of prioritisation, phase-out substances and risk reduction substances.

Phase-out Substances

Property

Classification according to the CLP regulation for determination of the intrinsic properties 

Carcinogenic   (Carcinogenicity, Category 1A and 1B)

H350: May cause cancer...* 

Mutagenic   (Germ cell mutagenicity, Category 1A and 1B)

H340: May cause genetic defects...* 

Toxic to reproduction  (Reproductive toxicity, Category 1A and 1B)

H360: May damage fertility or the unborn child…* 

Endocrine disrupter  (see the criteria in detail
Particularly hazardous metals (Cd, Hg, Pb)  (see the criteria in detail
PBT /vPvB – Persistent, Bioaccumulating, Toxic / very Persistent, very Bioaccumulating  (see the criteria in detail
Ozone-depleting substances (Hazardous to the ozone layer)

EUH059: Hazardous to the ozone layer

H420: Harms public health and environment by destroying ozone in the upper atmosphere. 

 

Priority Risk-reduction Substances

Property

Classification according to the CLP regulation for determination of the intrinsic properties 

Very high acute toxicity   (Acute toxicity, Category 1 and 2)

H330: Fatal if inhaled

H310: Fatal in contact with skin

H300: Fatal if swallowed

(Specific target organ toxicity after single exposure)

H370: Cause damage to organs.* and ** 

Allergenic  (Respiratory or skin sensitisation, Category 1, 1A and 1B)

H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.

H317: May cause an allergic skinreaction 

High chronic toxicity  (Specific target organ toxicity after repeated exposure)

H372: Cause damage to organs trough prolonged or repeated exposure.* and ** 

Mutagenic  (Germ cell mutagenicity, Category 2)

H341: Suspected of causing genetic defects...* 

Environmentally hazardous, long-term effects  (Hazardous to the aquatic environment, Chronic Category 1 and 4)

H410: Very toxic to aquatic life with long lasting effects.

H413: May cause long lasting harmful effects to aquatic life 

Potential PBT / vPvB  (see the criteria in detail

 

* If it is conclusively proven that no other routes of exposure cause the hazard, the route of exposure can be stated as a part of the hazard statement. Regarding reproductive toxicity the specific effect shall be stated if known (effect on fertility or the unborn child). One or two letters after the hazard statement indicate the route of exposure (e.g. H350i - May cause cancer by inhalation) and/or type of effect. All additional codes are included in the criteria.

** If known, all organs affected can be stated as a part of the hazard statement H370 or H372.